Touch Blocker is a simple but useful app that makes holding and using your device easier. There are two basic functions - it can create dead zones where touches do not register and also filter the screen when reading in low light.
This is a relatively stable Beta release. You can follow its progress at the XDA thread here: http://goo.gl/Tilmj
Please be sure to write with suggestions - we are looking forward to engaging the community and building a useful and nifty application that many will enjoy!